Effitix Dosage Calculator For Dogs
Determine the correct pre-measured topical size based on your dog’s weight.
Recommended Administration Details
- Do Not Split Tubes: Never buy a larger size pipette to divide between smaller dogs. Concentration distributes unevenly when poured manually, risking severe underdosing or toxic overdosing.
- No Manual Measuring: Never attempt to measure liquid amounts manually. Use only the full pre-measured tube size assigned to your dog’s weight band.
- Species Specificity: Designed strictly for dogs only.
Effitix dosage for Dogs is a combination of three active ingredients (fipronil, permethrin, and pyriproxyfen) applied topically and is effective against a variety of parasites for one month. These active ingredients work together to kill adult fleas, their eggs and larvae, ticks, lice, control sarcoptic mites (scabies mites), repel biting flies and repel and kill mosquitoes, including those that carry heartworm disease.
Quick dry non-greasy formulation is effective for up to 1 month and won’t wash off with bathing, using shampoo or water, rain, water immersion or normal sunlight exposure when used as directed on the product.
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Effitix medication is intended for use in dogs and puppies 8 weeks of age or older, and it is available in five different dose levels according to the weight of the dog (approximately 5 to 132 lb/ 2.3–60 kg). It is intended for use exclusively on dogs, and must never be used on cats because permethrin is highly toxic to cats. The most critical steps in successfully and safely controlling parasites are to select the proper pipette for the dog’s current weight and to give the entire pipette right on the dog’s body.
Always consult your veterinarian and the product label, particularly when your dog is pregnant, nursing, elderly or has an underlying health condition.
What is Effitix Dosage Dosage For Dogs?
Effitix Dosage for Dogs is a pre-measured, one dose topical flea and tick treatment that contains 6.1% Fipronil and 54.5% Permethrin and is based on your dog’s weight. Effitix is applied topically once every 30 days, and is available in five different weight bands, from the Toy Dog (0.44 mL for 5 – 10.9 lbs) to the Extra Large Dog (6.0 mL for 89-132 lbs).
For safety and efficacy, never divide tubes between pets, never manually measure liquids and dogs under 5 lbs/8 weeks of age should not use Effitix.
Effitix Dosage Chart For Dogs By Weight
Effitix is administered topically once every 30 days. Match your dog’s weight to the appropriate pre-measured pipette size below.
| Weight Category | Weight Range (lbs) | Weight Range (kg) | Pipette Volume | Active Ingredient Concentration |
| Toy Dogs | 5 – 10.9 lbs | 1.5 – 4 kg | 0.44 mL | Fipronil 6.1% w/v + Permethrin 54.5% w/v |
| Small Dogs | 11 – 22.9 lbs | 4 – 10 kg | 1.0 mL | Fipronil 6.1% w/v + Permethrin 54.5% w/v |
| Medium Dogs | 23 – 44.9 lbs | 10 – 20 kg | 2.0 mL | Fipronil 6.1% w/v + Permethrin 54.5% w/v |
| Large Dogs | 45 – 88.9 lbs | 20 – 40 kg | 4.0 mL | Fipronil 6.1% w/v + Permethrin 54.5% w/v |
| Extra Large Dogs | 89 – 132 lbs | 40 – 60 kg | 6.0 mL | Fipronil 6.1% w/v + Permethrin 54.5% w/v |
⚠️ Critical Safety Guidelines
- Under 5 lbs (1.5 kg) or under 8 weeks old: Do NOT use Effitix medicine. The concentration poses a severe toxicity risk to puppies or very small dogs.
- Over 132 lbs (60 kg): Do not estimate the dosage. Speak to your veterinarian about how to mix different pipettes to provide for your dog’s overall weight.
- Never Split Pipettes: Don’t purchase a big tube to use for smaller dogs. When manually pouring, active ingredients are not distributed evenly which can lead to an overdose or insufficient dose.
What is Effitix Plus for Dogs?

Effitix Plus for Dogs is a broad spectrum monthly topical spot-on treatment for dogs and puppies 8 weeks and older, to help protect against a wide range of external parasites. It is a combination of the active ingredients fipronil and permethrin, which kill and repel parasites upon contact, therefore, the treatment doesn’t need to be bitten in order to work.
Effitix Plus dosage for dogs offers full protection; killing adult fleas, flea eggs, flea larvae, ticks and lice; repelling and killing mosquitoes; repelling biting flies; and helping control sarcoptic mites (mange mites). Active against a variety of common tick species, such as brown dog ticks (Rhipicephalus sanguineus), American dog ticks (Dermacentor variabilis), lone star ticks (Amblyomma americanum) and deer ticks (Ixodes scapularis).
The fast-acting formula acts on the tick upon contact, and the repellency lasts for 10 minutes or less, helping to reduce the risk of disease transmission. It is effective against fleas (adults) for a minimum of 6 hours, and at least 99.6% of the flea population is killed within 12 hours, and also provides rapid tick control, at least 98% of four tick species is killed 9 days after treatment.
Furthermore, it will not only repel and kill mosquitoes that may be carrying heartworm disease, but it has been proven to achieve a greater than 77% anti-feeding effect on mosquitoes for up to 4 weeks (28 days).
Can provide up to 30 days protection from biting flies, mosquitoes, fleas, ticks and lice. This topical solution is effective after water immersion, swimming, rain, bathing and normal sunlight exposure, ideal for active dogs. Effitix Plus should only be used on dogs and never on cats.
Effitix Plus Topical Solution for Dogs Uses
Effitix Plus Topical Solution for Dogs is a broad-spectrum, monthly topical solution for dogs that helps protect against a variety of external parasites, for dogs and puppies 8 weeks of age and older. It is formulated with the combination of three active ingredients – fipronil, permethrin and pyriproxyfen – that kill parasites on contact, prevent new ones from getting in and stay effective for up to one month.
Quick drying, non-greasy formula is active after bathing, swimming, rain, water immersion and regular sunlight exposure.
What is Effitix Plus used for?
Effitix Plus is typically found in use to:
- Kill and repel adult fleas
- Dedicate the time to destroy flea eggs and flea larvae, and avoid the emergence of additional flea stages
- All kill and repel ticks, including brown dog ticks, American dog ticks, lone star ticks and deer ticks.
- Eliminate chewing and biting lice; reduce liability of a lice infestation.
- Help control Sarcoptes mites that can lead to sarcoptic mange
- Deter biting flies and minimise their blood feeding
- Prevent & kill mosquitoes that could be carrying the heartworm disease
Key benefits of Effitix Plus For Dogs

- You don’t need fleas and ticks to bite your dog, just as your medication doesn’t need to be administered by a bite.
- Effective in killing more than 90% of fleas in 6 hours and 99.6% in 12 hours.
- Starts to repel ticks, thus lowering the risk of disease transmission from ticks within 10 minutes.
- Kills 98% of the 4 labeled tick species or more as early as 9 days after treatment.
- Helps prevent new flea and tick infestations and stops existing infestations for up to 1 month.
- Helps prevent parasites which can cause diseases like Lyme, Rocky Mountain Spotted Fever, Ehrlichiosis, Anaplasmosis, Babesiosis, Bartonellosis, Tapeworms, Tularemia and Heartworm Disease.
- Can help decrease the risk of Flea Allergy Dermatitis (FAD) and flea-bite anemia associated with flea infestation.
One application every month for convenient and long lasting protection from parasites with Effitix Plus. But while it can repel and kill mosquitoes who will transmit heartworm disease, it’s not a substitute for a veterinarian prescribed heartworm preventive. Only to be used on dogs and puppies from 8 weeks of age and never on cats.
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Topical Solution for Dogs Ingredients:
Effitix Plus Dosage for Dogs has 3 actives that combine for broad-spectrum protection against fleas, ticks, lice, mosquitoes and other external parasites. Each ingredient is responsible for killing or preventing the parasites and the other inactive ingredients help to effectively deliver the topical solution.
Active ingredients
- Fipronil – 6.0%
Kills fleas and ticks on contact, which helps to eliminate an infestation without the flea or tick biting your dog. - Permethrin – 44.8%
Prevents ticks, mosquitoes, biting flies from contacting the skin and killing them, which decreases blood-feeding and the likelihood of diseases transmitted by parasites. The permethrin in Effitix Plus has a cis/trans ratio of a maximum of 55% (±) cis and a minimum of 45% (±) trans. - Pyriproxyfen – 1.8%
An insect growth regulator (IGR) that can kill flea eggs and stop the flea larvae from developing into adult flea helps to break the flea life cycle.
Complete formulation
| Ingredient | Concentration |
|---|---|
| Fipronil | 6.0% |
| Permethrin | 44.8% |
| Pyriproxyfen | 1.8% |
| Other (Inactive) Ingredients | 47.4% |
| Total | 100.0% |
Fipronil, permethrin and pyriproxyfen work together to kill adult fleas, ticks and lice, repel mosquitoes and biting flies, and prevent new infestations of fleas from developing, all in one monthly application.
What to Know Before Using Effitix Plus Topical Solution for Dogs
Ensure you read the important safety information before using Effitix Plus Topical Solution for Dogs so that it is effective and safe for your dog.
Important precautions
- Only use on dogs and puppies 8 weeks of age and older.
- Effitix Plus is not safe for use on cats.
- Do not apply more than once a month. It is not recommended to use the product more often than indicated.
- Avoid bathing for 24 hours after application as this can affect the effectiveness of the product.
- In cases of skin irritation, skin disease or if your dog is under treatment for skin disease, seek veterinary advice before applying any topical flea and tick treatment.
- Do not allow children or other animals to come in contact with the product before it has been used safely.
Additional things to know
Effitix Plus:
- Kills and repels fleas, ticks, biting flies, mosquitoes, and lice.
- Reduces Sarcoptes mites that cause sarcoptic mange.
- Acts on contact without the need for fleas and ticks to bite your dog.
- Helps to halt and prevent new parasite infestation and stop existing infestations.
- Contains a rapid-dry, water-repellent formula that lasts for a month.
Environmental safety
Dispose of used applicators and leftover product following your local waste disposal guidelines. Effitix Plus can be harmful to fish and wildlife; do not pollute ponds, streams or water bodies while using or disposing of.
Directions for Use

It is important to use Effitix Plus Topical Solution for Dogs properly in order to ensure safe and effective protection against parasites. Please read the full product label and follow all instructions prior to application. Any use other than that which is specified on the label is illegal under Federal law.
Before you apply
- For external use only: dogs and puppies 8 weeks of age and older, and weighing at least 5 lbs (2.3 kg).
- Always weigh your dog to get the correct dose for your dog’s weight. An overdose or under dose may lead to severe health consequences.
- Before using, ask your vet’s advice if your dog has a skin condition or is receiving treatment for one.
How to apply Effitix Plus
- Take one applicator out of the box, keeping it upright.
- Remove the cap, invert and reattach the other end to the applicator tip.
Push the cap down firmly to break the seal and remove cap. - Section your dog’s coat so that you can see their skin.
- Rub the applicator tip directly on the exposed skin and NOT on the hair.
- Squeeze the applicator until all the fluid has been dispensed as per your dog’s weight.
Important: Do not apply Effitix Plus only to the dog’s hair, but to the skin, otherwise the product will be ineffective.
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FAQs
Is there any fipronil in Effitix Plus?
Yes. Effitix Plus contains fipronil (6.0%) and permethrin (44.8%) and pyriproxyfen (1.8%) that will kill and repel fleas, ticks, mosquitoes and other external parasites.
Can Effitix Plus be used in dogs that have had seizures?
Consult your veterinarian before using Effitix Plus if your dog has ever had an episode of seizures or any neurological disorder. Your veterinarian can assess whether or not this product is right for your pet’s health.
What are the side effects of Effitix Plus?
Mild skin irritation, redness or discomfort may occur at the site of the application in some dogs. If your pet is on medications or supplements, inform your veterinarian prior to using Effitix dosage for dogs. Avoid use on small mammals, rabbits, etc. as it can be toxic to them.
What should be the frequency of using Effitix Plus?
Effitix Plus dog dosage can be used on a monthly basis following the product instructions. Wash hands well with soap and water after using.
Will I get the same Effitix Plus product as the one I see displayed on the internet?
If you buy from a good retailer, you can expect the same brand and product that you ordered, although the packaging may sometimes differ with Effitix Plus.
Is it necessary to use up all of the applicator?
Yes. Every applicator contains one dose that is pre-measured to fit your dog’s weight range. Use all of the product at once each month it is applied to do what it is supposed to do.
Can I discontinue the use of Effitix Plus after my dog has no more fleas?
Flea treatment every month can help prevent re-infestations even after the fleas have been eliminated. Your veterinarian will be able to tell you how long your dog should be taking Effitix Plus depending on your pet’s lifestyle and level of exposure to parasites.
Are there any medicines that cannot be used together with Effitix Plus?
Always check with your veterinarian about using Effitix Plus in conjunction with other drugs or supplements to ensure they are safe together.
Key Takeaways
- Effitix Plus is a topical treatment for dogs applied every month to prevent flea, tick, lice, mosquito, biting fly and Sarcoptes mite control.
- It has three active ingredients: fipronil (6.0 %), permethrin (44.8 %) and pyriproxyfen (1.8 %).
- The formula is contact, meaning that fleas and ticks don’t have to bite your dog for it to take effect.
- Effective for up to 1 month after application and is still effective when exposed to bathing, swimming, rain and under normal sunlight exposure.
- For use in dogs and puppies 8 weeks of age and older and 5 lbs (2.3 kg) or more.
- Always use the right applicator for the appropriate weight, and apply the product directly to the skin.
- Do not apply Effitix Plus to cats, rabbits or other small mammals as it could be harmful to these species.
- There may be some mild skin irritation at the application site. If your dog has previously been diagnosed with a skin condition or seizures talk to your veterinarian before using.
- A mosquito repellent should not be a substitute for a prescribed heartworm program; follow your veterinarian’s heartworm treatment program (if applicable).
- Take care to follow the product label and apply no more often than once in 30 days, for safe and effective parasite control.
Final Thoughts
Effitix Plus Topical Solution dosage for Dogs is a monthly topical treatment that is broad spectrum, providing reliable protection against the 6 most common parasites – flea, tick, lice, mosquito, biting fly and Sarcoptes mite.
Because it contains a mixture of fipronil, permethrin and pyriproxyfen, it works to stop flea infestations as well as kill the parasites that are already present in the household. Fast-acting, waterproof, and long-lasting, it’s hassle-free protection for active dogs all month long.
For most effective results, always weigh your dog, choose the correct size applicator for your dog’s weight, and apply the full amount to the skin every 30 days. Please note: Effitix Plus is intended for use in dogs only and is not intended for use in cats. However, if your dog is already suffering from any health issues, skin issues or a history of seizures, then speak to your veterinarian before beginning treatment.
Effitix Plus can be an effective component of your dog’s year round parasite prevention program when used as directed on the product label and according to your veterinarian’s advice.














