Activyl Dosage Calculator For Dogs
Recommended Administration Plan
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When using Activyl Dosage for dogs, it is essential that you know how it works, which dogs it is for, and how to apply it safely. Activyl® is a monthly spot-on flea treatment for dogs that contains indoxacarb (19.53%) which is an FDA approved antiparasitic compound that kills fleas on contact without causing them to bite your dog. Activyl’s unique bioactivation mechanism occurs when the treated coat comes in contact with the flea; the enzymes in the flea transform indoxacarb into its active form, which then penetrates the insect’s nervous system, leading to death, and only a small amount is activated in mammals.
Activyl medication spreads on the natural oils on the skin and in the coat after application, but does not enter the bloodstream, giving up to 30 days of protection against fleas. It is effective in killing adult fleas in about 8 hours, killing developing stages of flea life cycle, and inhibiting the development of flea eggs and larvae, which helps prevent future infestations. The product will last for the entire month and will continue to work even after your dog swims or bathes.
Activyl Dosage comes in various doses according to body weight so it is important to use the appropriate pipette size for safety and effectiveness. In this guide, you’ll find an easy-to-use Activyl dosage for dogs calculator, weight-based dosage chart, proper application instructions, benefits, possible side effects, safety precautions, and answers to common questions to help you use Activyl correctly and protect your dog from fleas year-round.
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What is Activyl Dosage For Dogs?
Activyl dosage for dogs is a weight-based, once-monthly topical spot-on treatment used to control and prevent flea infestations in dogs. The standard Activyl dosage ranges is from 100 mg to 900 mg of indoxacarb, depending on your dog’s body weight. Dogs weighing 4–14 lb (1.8–6.5 kg) receive 100 mg (0.51 mL), 14–22 lb (6.6–10 kg) receive 150 mg (0.77 mL), 22–44 lb (10–20 kg) receive 300 mg (1.54 mL), 44–88 lb (20–40 kg) receive 600 mg (3.08 mL), and 88–132 lb (40–60 kg) receive 900 mg (4.62 mL).
For dogs requiring Activyl Tick Plus, the dosage also varies by weight and includes both indoxacarb and permethrin for added tick control. Always choose the correct pipette size based on your dog’s current weight and use it once every 30 days as directed by your veterinarian or the product label.
Activyl Dosage For Dogs Charts By Weight
Here are the reference dosage tables for both product lines based on your provided guidelines:
Activyl Dosage Chart for Dogs (Standard)
Designed as a once-month topical spot-on treatment containing Indoxacarb.
| Body Weight (Pounds) | Body Weight (Kilograms) | Pipette Volume (mL) | Indoxacarb Dose (mg) |
| 3.3 to 14.3 lbs | 1.5 to 6.5 kg | 0.51 mL | 100 mg |
| 14.5 to 22 lbs | 6.6 to 10 kg | 0.77 mL | 150 mg |
| 22.2 to 44 lbs | 10.1 to 20 kg | 1.54 mL | 300 mg |
| 44.3 to 88 lbs | 20.1 to 40 kg | 3.08 mL | 600 mg |
| 88.4 to 132 lbs | 40.1 to 60 kg | 4.62 mL | 900 mg |
Note for Dogs Over 60 kg (132 lbs): Dosing by dog weight dictates combining two pipettes simultaneously to safely match the exact weight of the dog and reach the 15 mg/kg target (for example, a 70 kg dog requires one 10.1–20 kg pipette combined with one 20.1–40 kg pipette).
Activyl Tick Plus Dosage Chart for Dogs
Designed as a once-month topical spot-on treatment containing Indoxacarb and Permethrin.
| Body Weight (Pounds) | Body Weight (Kilograms) | Pipette Volume (mL) | Indoxacarb Dose (mg) | Permethrin Dose (mg) |
| 2.6 to 11 lbs | 1.2 to 5 kg | 0.5 mL | 75 mg | 240 mg |
| 11 to 22 lbs | 5 to 10 kg | 1.0 mL | 150 mg | 480 mg |
| 22 to 44 lbs | 10 to 20 kg | 2.0 mL | 300 mg | 960 mg |
| 44 to 88 lbs | 20 to 40 kg | 4.0 mL | 600 mg | 1,920 mg |
| 88 to 132 lbs | 40 to 60 kg | 6.0 mL | 900 mg | 2,280 mg |
What Is Activyl For Dogs?
Activyl® Dosage For Dogs is a topical once-monthly flea treatment for dogs that contains the insecticide indoxacarb which provides targeted control of fleas through a unique bioactivation process. Flea are not required to bite to be affected by Activyl, unlike many traditional flea treatments that need to be bitten to be effective.
Activated immediately kills adult fleas, eggs, and larvae, disrupts their nervous system, and helps to prevent feeding and reinfestation. Activyl dosage can be used to control cat fleas (Ctenocephalides felis); Activyl Tick Plus is a combination of the flea-control ingredient, indoxacarb, and an added tick-control ingredient to protect against both fleas and ticks.
Activyl is a Merck product that provides month-long protection, and is intended to help maintain dogs without the presence of flea infestations for 30 days per application.
Benefits of Activyl for Dogs
Activyl medication is a topical spot-on flea treatment that offers targeted, fast and long-lasting protection for up to 30 days. It’s a special bioactivated formula that begins to work the minute it is applied, and can help prevent another flea infestation.
Key benefits include:
- Quick acting formula that can kill as many as 90% of fleas after just 12 hours.
- Eliminates fleas from your dog without them having to bite.
- Tackles the flea life cycle by attacking the flea life stage at three places—adults, eggs and larvae.
- Kills all the newly arrived fleas for up to 4 months, giving monthly protection.
- Specifically directed action in order to achieve effective control of flea infestations.
- Convenient, non-refusable topical spot-on application, which is quick and easy to apply, unlike oral medicines.
- Helps prevent reinfestation by minimizing the opportunity for flea breeding in your dog’s environment.
Are there any side effects to Activyl?
When used as directed, Activyl is generally safe and well tolerated, however, like any medication can have side effects in some dogs. Most reactions are short-lived, and are not severe around the application site. Though rarely seen, any serious reactions should be addressed with your veterinarian.
Frequent side effects of Activyl for Canines are:
- Increased salivation (dripping salvia) for a short time after application.
- Mild skin irritation at area of application.
- Squinting or discomfort in eyes.
- Head shaking.
- Rubbing or scratching affected area.
- For up to 24 hours post treatment the application site may be wet or oily.
Other side effects reported for Activyl Tick Plus:
- Temporary redness of the skin (erythema).
- Itching (pruritus).
- Loss of hair at the application area.
- Lethargy.
- Mild gastrointestinal symptoms such as diarrhea.
Precautions
- Avoid use in dogs that have been diagnosed with an allergy or hypersensitiveness to the components of Activyl.
- Only for dogs 8 weeks of age or older and 4 lb (1.8 kg) or more. Activyl Tick Plus for dogs can be used on dogs 8 weeks of age or older and 2.6 lb (1.2 kg) or more.
- Not recommended for pregnant or lactating dogs unless advised by your veterinarian.
- Let your vet know if your dog is on any other medication or supplements, as there can be drug interactions.
- Temporary salivation, licking, vomiting, head shaking and even squinting can occur if your dog licks/swallows the product. If symptoms are severe or do not improve, please get advice from your vet.
Why is it important to take precautions when using Activyl?
Activyl dose for dogs properly used makes for safe and effective flea control. Please read and obey these precautions before using it on your dog.
General precautions
- For topical use only—do not administer orally.
- Thoroughly wash hands after product use.
- Out of reach of children & animals.
- Not for human use.
- Don’t let your dog or other pets lick the application area until dry.
Activyl for Dogs precautions
- Activyl for Dogs should NOT be used on cats.
- Only use in dogs and puppies 8 weeks of age and 4 lb (1.8 kg) or more.
- Avoid in pregnant, nursing and breeding dogs.
Activyl Tick Plus precautions
- Do not use on cats as it is only for dogs.
- Only use in dogs and puppies 8 weeks old and 2.6 lb (1.2 kg) or more.
- Avoid in pregnancy, lactating and breeding dogs.
By following these precautions and applying the right product for the right weight range, the risk of side effects is minimised, and Activyl is effective.
What’s the efficacy of Activyl and Activyl Tick plus?
Activyl and Activyl Tick Plus are two highly effective topical flea control treatments for dogs that can be used on a monthly basis. Both products work within 8-12 hours and your dogs will no longer allow fleas to feed them, immobilize them, or kill adult fleas.
Actively prevents flea egg development into larvae for 4 weeks, in addition to killing developing flea stages in your dog’s home environment and preventing reinfestation for at least 4 weeks, which helps to break the flea life cycle.
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Activyl for Dogs
- Begins to kill fleas in 8-12 hours.
- Prevents flea feeding and results in killing of adult fleas.
- Removes flea eggs and immature larvae from dog’s environment.
- Offering 4-weeks of ongoing flea control.
Active Insecticide Tick Plus for Dogs
- Controls cat fleas (Ctenocephalides felis) for up to 4 weeks.
- Provides tick control against:
- For up to 5 weeks, Ixodes ricinus.
- Rhipicephalus sanguineus for up to 3 weeks.
- Although some existing ticks may not die in the first 48 hours, they can be killed in one week.
- Kills developing stages of fleas in the dog’s immediate environment to help prevent new infestations.
Apply Activyl Spot-On for Dogs:
Correct use of Activyl helps to assure optimal flea control.
- Take one out of the foil pack.
- Keep the applicator up and out of the way of your face.
- Bend and fold the applicator tip back to open it up.
- Divide hair to expose skin.
- Apply the whole mixture to the skin.
- Give it time to fully dry.
- Rinse hands with soap and water after use.
If you are looking to download the application based on the size of your dog, you can find it here.
- Small dogs: Apply the entire dose between the shoulder blades.
- Medium and large dogs: Use the whole dose, evenly distributed on 2-4 spots from the shoulder blades to the base of the tail. Divide and apply directly to skin, at each location.
Why Choose Activyl for Dogs?
There are several reasons for using Activyl dose long-term for flea control.
- Starts killing fleas within 8–12 hours.
- Kills almost all fleas in 12 hours after application.
- Gives protection for up to 4 weeks after one monthly injection.
- Kills adult fleas, eggs and larvae to break the flea life cycle.
- The treatment doesn’t require fleas to bite your dog.
- Fast-drying topical formula.
- Fragrance-free application.
- Resists water and will not break down after bathing or typically using the sun.
- Easy monthly spot-on treatment.
- Bioactivation, increases activity only in the flea, for targeted control of fleas.
- Assists in minimizing problems from fleas, flea allergy dermatitis and flea-associated tapeworm transmission.
How to Use Activyl Safely
To achieve best results:
- Once every 30 days.
- Do not apply more than one applicator per month.
- Always read and follow the directions on the label.
- Wash hands after using.
- Avoid contact with treated area until dry.
- Only use the correct weight based applicator for your dog.
Important Warnings and Storage
Warnings
- Used on the outside of the body only.
- If swallowed or absorbed through the skin, may be harmful.
- Do not get in eyes or clothing.
- Avoid giving to children.
- Keep pets away from the treated area until it is dry, and do not let pets lick the treated area.
- Can cause temporary eye irritation if it comes into contact with the eyes.
Storage
- Keep out of direct sunlight and moisture.
- Do not handle by children or pets.
- Throw away empty applicators in the trash or recycle bin, when possible.
- Never pour unused product in the indoor or outdoor drains.
You May Also Like to Read:
- Banamine Dosage For Dogs: Calculator and Safe Dosage Guide
- Cardalis Dosage For Dogs: Calculator, Chart & Safe Guide
FAQs
What does Activyl dosage do for dogs?
Activyl is a topical monthly flea treatment that contains indoxacarb. It provides adult flea kill, acts on developing flea stages and aids in the disruption of the flea life cycle to avoid re-infestation.
How many times a day can I give Activyl medication to my pet?
Activyl dosage should be applied at 30 day intervals. Never give more than once a month, unless your veterinarian instructs you to do so.
How quickly does Activyl start working?
After around 8 hours, Activyl will kill fleas and most fleas will be killed within 8 to 12 hours of application.
Does Activyl kill flea eggs and larvae?
Yes. Activyl also kills developing flea stages – eggs and larvae – which can help stop the flea life cycle and further cut down on future flea infestations.
Is it okay to let my dog get wet after applying Activyl?
Yes. After drying completely, Activyl’s waterproof formulation stays active after regular bathing and swimming. Don’t bathe your dog until the application area is dry.
Are puppies safe to use Activyl?
Yes, but only for puppies 8 weeks of age and 4 lb (or 1.8 kg) or more. Always use the proper weight based applicator.
If my dog licks Activyl what should I do?
If it is licked by your dog, it is possible for him or her to drool, shake their head, squint or vomit. If you notice symptoms are severe or symptoms do not go away, please reach out to your veterinarian.
What is the difference between the two products, Activyl and Activyl Tick Plus?
Activyl is a product that kills only fleas, but Activyl Tick Plus contains the ingredient indoxacarb and the ingredient permethrin to kill fleas and some tick species. Follow the product recommendations for your dog and don’t give Activyl Tick Plus to cats.
Key Takeaways
- Activyl is a topical flea treatment for dogs that is given monthly and contains indoxacarb.
- Always use the correct pipette size as dosage is by bodyweight.
- The typical dosage of Activyl for dogs is 100 – 900 mg of indoxacarb for each 4 – 132 lb (1.8 – 60 kg) of body weight.
- For long-term continuous protection, apply Activyl every 30 days.
- Activyl Tick Plus is a weight-based flea/tick treatment that contains indoxacarb and permethrin.
- Medication begins to kill off the fleas in approximately 8 hours and helps to break the flea life cycle by controlling developing flea stages.
- Topical solution does not enter the bloodstream, and is effective after normal bathing or swimming.
- Never divide or combine pipettes to make up different doses without your veterinarian’s specific instructions.
- Always use in accordance with veterinarian’s directions and product instructions for safe and effective use.
Final Thoughts
Activyl Dosage For dogs is a topical month-on-month flea treatment with a reliable active ingredient, indoxacarb, which helps prevent new flea infestations, stops the flea life cycle and kills adult fleas for up to 4 weeks. It is rapidly absorbed by the dog and controls fleas without having to bite it when applied according to the label directions and your dog’s body weight.
Activyl Tick Plus also offers extra protection against some ticks for dogs requiring tick protection. For optimal efficacy, use the appropriate weight based applicator, apply once every 30 days, and as recommended by your veterinarian. If your dog has some unusual effects or you have any concerns about the treatment, call your veterinarian immediately.
