Zenrelia® Dosage Calculator For Dogs
Accurate Once-Daily Ilunocitinib Dosing for Dogs (12 Months or Older)
Minimum weight requirement for Zenrelia treatment is 6.6 lbs (3.0 kg).
© medsdog.com
Always ask your vet for Zenrelia Dosage for dogs. Zenrelia® (ilunocitinib) is a prescription medicine for dogs to treat the signs of allergic dermatitis and to relieve itching associated with atopic dermatitis. By targeting the inflammatory pathways that cause itching and skin irritation, it can provide many dogs with noticeable relief and enhance their comfort and quality of life.
Paid Links - As an Amazon Associate, I earn from qualifying purchases.
Zenrelia medication comes as a tablet to take by mouth once a day, with or without food, for easy home long-term use. It can be used in dogs over 12 months old, and should never be dosed without veterinary guidance. Just as with any drug, Zenrelia can have side effects, the most common being vomiting, diarrhea, and lethargy (tiredness).
To use Zenrelia for dogs safely and effectively for your dog, you will find a Zenrelia dosage calculator based on veterinary advice, a Zenrelia dosage chart for dogs by weight, administration tips, potential side effects, safety precautions and answers to frequently asked questions in this guide.
Disclaimer: This guide is for informational purposes only and is not a substitute for professional veterinary advice.
Always consult your veterinarian before giving Zenrelia or any medication to your dog.
Key Takeaways
- Zenrelia® (ilunocitinib) is a prescription drug that is used to relieve itching from allergic dermatitis and to control atopic dermatitis in dogs.
- The correct dosage of Zenrelia for dogs always depends on the needs of your dog and should be determined by a vet.
- Zenrelia dosage for dogs can be taken with or without food and is given orally once a day as tablets.
- Can be used on dogs 12 months and over.
- The medication is effective because it helps to diminish the inflammatory reaction that is responsible for itching and irritation of the skin.
- Many dogs tolerate the medication well and common side effects include vomiting and diarrhea, and lethargy (tiredness).
- Do not increase or decrease the dosage or discontinue use without veterinary supervision.
- Watch your dog closely for any abnormal response and consult your vet if your dog’s symptoms get worse or are severe.
Zenrelia Dosage Chart For dogs By Weight
Here is the accurate, official weight-bracket and tablet dosage guide for Zenrelia (ilunocitinib) once-daily administration in dogs.
- Target Dose Range: 0.6 mg to 0.8 mg per kg of body weight (0.27 mg to 0.36 mg per lb)
- Minimum Requirements: Dogs must be at least 12 months of age and weigh at least 6.6 lbs (3.0 kg).
| Dog Weight in Pounds (lbs) | Dog Weight in Kilograms (kg) | Recommended Tablet Administration Plan (Once Daily) |
| 6.6 to 8.8 lbs | 3.0 to 4.0 kg | Give half (0.5) of a 4.8 mg tablet |
| 9.0 to 11.7 lbs | 4.1 to 5.3 kg | Give half (0.5) of a 6.4 mg tablet |
| 11.9 to 14.3 lbs | 5.4 to 6.5 kg | Give half (0.5) of a 8.5 mg tablet |
| 14.6 to 17.6 lbs | 6.6 to 8.0 kg | Give one (1) 4.8 mg tablet |
| 17.9 to 23.4 lbs | 8.1 to 10.6 kg | Give one (1) 6.4 mg tablet |
| 23.6 to 31.1 lbs | 10.7 to 14.1 kg | Give one (1) 8.5 mg tablet |
| 31.3 to 35.3 lbs | 14.2 to 16.0 kg | Give one and a half (1.5) 6.4 mg tablets |
| 35.5 to 43.0 lbs | 16.1 to 19.5 kg | Give one and a half (1.5) 8.5 mg tablets |
| 43.2 to 54.9 lbs | 19.6 to 24.9 kg | Give one (1) 15 mg tablet |
| 55.1 to 62.4 lbs | 25.0 to 28.3 kg | Give two (2) 8.5 mg tablets |
| 62.6 to 82.5 lbs | 28.4 to 37.4 kg | Give one and a half (1.5) 15 mg tablets |
| 82.7 to 110.0 lbs | 37.5 to 49.9 kg | Give two (2) 15 mg tablets |
| 110.2 to 137.6 lbs | 50.0 to 62.4 kg | Give two and a half (2.5) 15 mg tablets |
| 137.8 to 165.1 lbs | 62.5 to 74.9 kg | Give three (3) 15 mg tablets |
Safety Notice: For giant breed dogs weighing 165.3 lbs (75.0 kg) or more, veterinarians should use a calculated combination of tablet strengths to safely stay within the targeted 0.6–0.8 mg/kg range.
What Is Zenrelia?
Zenrelia® (ilunocitinib tablets) is a prescription medicine for dogs which has been approved by FDA to help control pruritus (itching) associated with allergic dermatitis and manage signs of atopic dermatitis. Zenrelia dosage for dogs is a Janus kinase (JAK) inhibitor and contains the drug ilunocitinib, which is an immune-modulating drug that helps to diminish the inflammatory response that causes itchy, irritated skin.
Zenrelia is for use in dogs 12 months or older and is dosed by body weight at 0.6 – 0.8 mg/kg as an oral tablet once per day. Reduces overgrooming, scratching, chewing and biting, which is associated with allergic skin disease and causes discomfort in your dog and helps prevent hair loss and complications like secondary skin infections that can occur from excessive scratching. Zenrelia is a prescription only medicine, and as such, should only be used under veterinary supervision.
What Is Zenrelia Used for in Dogs?
Zenrelia® (ilunocitinib) is a prescription drug that is used to treat allergic dermatitis and atopic dermatitis (eczema) in dogs 12 months of age and older for itching (pruritus) and inflammation. It is effective in blocking the cytokines that cause itching and inflammation to help relieve all the discomforts of an allergic reaction that affect the skin. Zenrelia is effective for symptom management, but is not a cure for the allergy and should only be used as directed by your veterinarian.
Zenrelia dose for dogs can be used for the short-term treatment of an allergy flare-up or as a long-term control of chronic allergic skin disease under veterinarian supervision. It comes as an unflavoured, hypoallergenic, oral tablet to be administered once a day and can be combined with other allergy medications like omega 3 supplements, flea prevention, hypoallergenic diets or medicated shampoos.
Zenrelia is a drug used to treat:
- Allergic atopic dermatitis from environmental allergens like pollen, dust, mold and grass.
- A type of allergic dermatitis causing chronic itching and inflammation of the skin.
- Ectoparasite hypersensitivity such as flea allergy dermatitis.
- Dermatitis, an allergic reaction to certain protein in the food eaten.
- Contact dermatitis from direct contact with irritants such as plants, chemicals, or fabrics.
Your vet can decide if Zenrelia is an appropriate treatment depending on your dog’s particular allergy and skin problem; the product can be used for dogs over 12 months of age and is approved by the FDA.
Benefits of Zenrelia for Dogs
Zenrelia® provides effective relief for dogs with skin conditions associated with allergy by reducing itching and inflammation associated with allergic dermatitis and helps to control the signs of atopic dermatitis.
It contains the active ingredient, ilunocitinib, which helps reduce inflammation and the inflammatory pathways that cause allergic itch, helping dogs feel more comfortable and preventing excessive scrching that could lead to a greater amount of skin damage.
Zenrelia’s Key Benefits
- Gives good relief of itching from allergic dermatitis.
- Helps control the signs of atopic dermatitis.
- Helps to decrease inflammation related to allergic skin disorders.
- Composed of the active ingredient, ilunocitinib, that acts on the immune response that causes itching.
- Delivered in a once-daily, hypoallergenic, unflavored oral tablet for easy administration.
- Is administered with or without food which makes it easier to take the medication daily at home.
Zenrelia drug for dogs is usually tolerated well but some dogs may vomit, have diarrhea or be lethargic (tired). Veterinarians will always give their recommendations and the product label will contain information about its safety and usage.
Possible Side Effects of Zenrelia for Dogs
As with any prescription drug, Zenrelia® may have side effects in some dogs. Most effects are only mild and short lasting, but more severe side effects have been seen in clinical studies. Please always follow your veterinarian’s advice and talk to your veterinarian if your dog shows persistent or severe symptoms while under Zenrelia.
Common Side Effects
- Vomiting
- Diarrhea
- Nausea
- Decreased appetite
- Lack of energy (lethargy or tiredness)
Less Common Side Effects
- Eye discharge
- Urinary tract infection (UTI)
- Low level of white blood cells
- Cough, wheeze, upper respiratory infection, or trouble breathing.
- Sneezing
- High levels of liver enzymes
- Bacterial skin infection
- Ear infection (otitis externa)
- Weight gain
- Increased thirst
Benign and malignant developments (including cancer) and infections were also noted in some of the dogs treated with Zenrelia during clinical studies. If your dog displays unusual symptoms, deteriorating symptoms or side effects that don’t improve, seek veterinary advice quickly to assess and manage.
Paid Links - As an Amazon Associate, I earn from qualifying purchases.
Zenrelia Overdose Concerns in Dogs
Excessive dosing of Zenrelia® can lead to more serious side effects and the severity of the effects will depend on the amount of the drug administered in comparison to the size of the dog and the length of time of the overdose. Overdose symptoms can include heightened effects of the medication’s common side effects, or more serious health problems with repeated overdoses or a large overdose.
Signs of a Zenrelia Overdose
- Heavy vomiting or diarrhoea
- Lethargy (low energy)
- Loss of appetite
- Symptoms of infection as a result of the immune suppression
- Deep infections between the toes (interdigital dermatitis) and swollen paws.
- Enlarged lymph nodes
- Between toes papilloma growths
- Low red blood cell count, low hematocrit (HCT), and low hemoglobin (Hgb)
- Depressed immune system
- Pneumonia
- Opportunistic infections are more likely to occur.
If you think your dog may have taken too much Zenrelia, be sure to contact your veterinarian or animal poison control center right away. Early veterinary attention is key to minimising risks of complications. Carry the medication container or prescription information if possible to help your veterinarian calculate the amount of medication your dog ingested and to treat your dog accordingly.
You May Also Like to Read:
- Onsior Dosage For Dogs: Calculator, Chart & Safe Guide
- Apple Cider Vinegar Dosage for Dogs: Calculator & Safe Guide
FAQs
How to Store Zenrelia dose for Dogs
Keep Zenrelia at room temperature (15-25°C or 59-77°F). Short-term temperature changes from 41°F (5°C) to 104°F (40°C) are acceptable. Store in its original container until it is time to use it and in a dry place at room temperature that is not too hot or humid. Always keep Zenrelia out of reach of children and pets.
Is Zenrelia Dosage Safe For Dogs?
Yes. When used as directed by your veterinarian, Zenrelia is safe for healthy dogs 12 months or older and current on their vaccinations. It is contraindicated in the dog suffering from severe infections.
How soon will Zenrelia begin to work?
Zenrelia starts to work soon after it is taken as it is rapidly absorbed after oral administration. The onset of itch relief, however, may take some time (varying from dog to dog).
Can Zenrelia be used long term?
Yes. Zenrelia may be used to treat chronic conditions like atopic dermatitis for a long time. If your veterinarian prescribes the use of the medication when it is appropriate, there is no limit as to how long the medication can be used.
Is Zenrelia good for dog food allergies?
Yes. Zenrelia is labeled for the control of itching as a result of allergic dermatitis, including food allergy dermatitis. Clinical trials to obtain FDA approval included dogs with food allergies.
Does Zenrelia work like Apoquel?
Yes. Both Zenrelia and Apoquel belong to the class of drugs known as Janus kinase (JAK) inhibitors; they have different active ingredients. Zenrelia is administered once a day; Apoquel is usually administered twice a day for the first 14 days, and then once a day to maintain. Some dogs may respond better to either of the medications.
What’s Zenrelia made of?
Zenrelia is a synthetic Janus kinase (JAK) inhibitor called ilunocitinib that blocks an immune reaction that is part of the allergy reaction that causes itching. It is not a cortisone or antihistamine.
May I vaccinate my dog during its use of Zenrelia?
No. Vaccination should not generally be administered while your dog is on Zenrelia as the drug weakens the dog’s immune system, and may make the vaccine less effective or make your dog more susceptible to vaccine reactions. When therapy is discontinued, resume vaccination based on veterinarian’s recommendations.
Final Thoughts
Zenrelia® Dosage For Dogs By Weight is a convenient once-daily prescription drug that helps control itching associated with allergic dermatitis and to manage atopic dermatitis in dogs 12 months of age and older. When prescribed and administered correctly by your veterinarian, it can help alleviate your dog’s allergy symptoms, making him more comfortable and happier.
Each dog is unique in how they react to treatment, so it is essential that the proper dosage be followed, side effects be monitored and veterinary check-ups take place during therapy sessions. Contact your veterinarian before beginning or altering treatment if you have any questions regarding the proper Zenrelia dosage for dogs, any possible drug interactions or if it is not suitable for your dog. The safest and most effective use of Zenrelia is to make sure it is dosed properly and given under constant veterinary supervision.
